Analysis of Molecular Variance (AMOVA) of Y--Chromosome--Specific Microsatellites in Two Closely Related Human Populations

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چکیده

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Analysis of molecular variance (AMOVA) of Y-chromosome-specific microsatellites in two closely related human populations.

The analysis of seven Y-chromosome-specific microsatellite loci revealed a high level of polymorphism in two closely related human populations (Dutch, n = 89, and German, n = 70). Four of these loci were found to generate at least 77 different haplotypes, only 15 of which were shared by the two populations. These results demonstrate that highly informative PCR-based DNA typing of the Y chromoso...

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We have analyzed five microsatellite loci from the nonrecombining portion of the human Y chromosome in 15 diverse human populations to evaluate their usefulness in the reconstruction of human evolution and early male migrations. The results show that, in general, most populations have the same set of the most frequent alleles at these loci. Hypothetical ancestral haplotypes, reconstructed on th...

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ژورنال

عنوان ژورنال: Human Molecular Genetics

سال: 1997

ISSN: 0964-6906,1460-2083

DOI: 10.1093/hmg/6.5.828